It’s an accepted concept by now that taking antibiotics in order to quell an infection disrupts the personal microbiome, the population of microorganisms that we all carry around in our guts, and which vastly outnumbers the cells that make up our bodies. That recognition supports our understanding of Clostridium difficile disease — killing the beneficial bacteria allows C. diff room to surge and produce an overload of toxins — as well as the intense interest in establishing a research program that could demonstrate experimentally whether the vast industry producing probiotic products is doing what it purports to do.
But implicit in that concept is the expectation that, after a while — after a course of antibiotics ends — the gut flora repopulate and their natural balance returns.
Early evidence from my lab and others hints that, sometimes, our friendly flora never fully recover. These long-term changes to the beneficial bacteria within people’s bodies may even increase our susceptibility to infections and disease. Overuse of antibiotics could be fueling the dramatic increase in conditions such as obesity, type 1 diabetes, inflammatory bowel disease, allergies and asthma, which have more than doubled in many populations.
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- Antibiotics May Be Permanently Altering the Guts of Humanity By Clay Dillow (imullins89.wordpress.com)
- Antibiotics may be doing permanent harm, doctor says (healthzone.ca)
- Is our food safe enough? (katyakate.wordpress.com)
- Antibiotic Overuse May Be Bad for Body’s Good Bacteria (webmd.com)
- Overuse of Antibiotics Is Seen Behind Many Human Ills (livescience.com)